tyrosinekinaseinhibitors相关论文
Assessment of chronic renal injury in patients with chronic myeloid leukemia in the chronic phase re
Objective Long term tyrosine kinase inhibitors(TKIs)therapy may impact organ function and result in poor treatment outco......
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Concurrent TP53 mutations predict poor outcomes of EGFR-TKI Treatments in Chinese patients with adva
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Structure-based design and synthesis of L858R/T790M selective epidermal growth factor receptor inhib
Mutated epidermal growth factor receptor(EGFR)is a major driver of non-small cell lung cancer(NSCLC)....
Tyrosine kinases regulate cell proliferation,differentiation,death,and other physiological processes by mediating the ce......
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Role of Recursive Partitioning Analysis and Graded Prognostic Assessment on Identifying Non-Small Ce
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甲状腺癌的发生及进展与一系列的分子改变及信号通路的激活有关，这也是药物靶向治疗的基础。对于不可手术的局部晚期、转移性、难治......
目的 探索肺腺癌患者缓解深度与酪氨酸激酶抑制剂(TKI)类药物疗效的相关性.方法 收集2015年至2016年就诊于本院的初治且携带表皮生......
酪氨酸激酶是一类具有酪氨酸激酶活性的蛋白质，其异常表达与肿瘤的发生、侵袭、转移以及肿瘤新生血管的生成等密切相关。近年来以酪......
人类表皮生长因子受体(epiderma l growth factorreceptor, EGFR)是原癌基因C-erbB1的表达产物,属于酪氨酸激酶生长因子受体家族成......
Uncommon EGFR mutations in a cohort of Chinese NSCLC patients and outcomes of first-line EGFR-TKIs a
Objective:Data on the clinical activity of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) in ......
Liver cancer accounts for 4.7％ of all newly diagnosed cancers and 8.2％ of cancer deaths annu-ally. Hepatocellular carcinom......
